Centromeric Retroelements and Satellites Interact with Maize Kinetochore Protein CENH3
نویسندگان
چکیده
منابع مشابه
Centromeric retroelements and satellites interact with maize kinetochore protein CENH3.
Maize centromeres are composed of CentC tandem repeat arrays, centromeric retrotransposons (CRs), and a variety of other repeats. One particularly well-conserved CR element, CRM, occurs primarily as complete and uninterrupted elements and is interspersed thoroughly with CentC at the light microscopic level. To determine if these major centromeric DNAs are part of the functional centromere/kinet...
متن کاملArabidopsis kinetochore null2 is an upstream component for centromeric histone H3 variant cenH3 deposition at centromeres.
The centromeric histone H3 variant cenH3 is an essential centromeric protein required for assembly, maintenance, and proper function of kinetochores during mitosis and meiosis. We identified a kinetochore null2 (KNL2) homolog in Arabidopsis thaliana and uncovered features of its role in cenH3 loading at centromeres. We show that Arabidopsis KNL2 colocalizes with cenH3 and is associated with cen...
متن کاملPoint mutation impairs centromeric CENH3 loading and induces haploid plants.
The chromosomal position of the centromere-specific histone H3 variant CENH3 (also called "CENP-A") is the assembly site for the kinetochore complex of active centromeres. Any error in transcription, translation, modification, or incorporation can affect the ability to assemble intact CENH3 chromatin and can cause centromere inactivation [Allshire RC, Karpen GH (2008) Nat Rev Genet 9 (12):923-9...
متن کاملDistribution of retroelements in centromeres and neocentromeres of maize.
Fluorescent in situ hybridization was used to examine the distribution of six abundant long terminal repeat (LTR) retroelements, Opie, Huck, Cinful-1, Prem-2/Ji, Grande, and Tekay/Prem-1 on maize pachytene chromosomes. Retroelement staining in euchromatin was remarkably uniform, even when we included the structurally polymorphic abnormal chromosome 10 (Ab10) in our analysis. This uniformity mad...
متن کاملPutting the cenH3 in the Centromere: Arabidopsis KINETOCHORE NULL2 Acts Upstream of cenH3 Deposition
Imagine yourself as a chromatin-crawling nano-robot—Your mission: to explore the Arabidopsis thaliana centromere. If you ventured from the euchromatin, through the heterochromatin, into the centromere, you would find yourself in a strange place. Even the histones are different, with the familiar H3 replaced by the centromerespecific histone cenH3 (reviewed in De Rop et al., 2012). Mission contr...
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ژورنال
عنوان ژورنال: The Plant Cell
سال: 2002
ISSN: 1040-4651,1532-298X
DOI: 10.1105/tpc.006106